Search results for " EVR"

showing 3 items of 3 documents

LOW VITAMIN D SERUM LEVEL IS RELATED TO RAPID, EARLY AND SUSTAINED VIROLOGICAL RESPONSE TO IFN-BASED THERAPY IN GENOTYPE 1 CHRONIC HEPATITIS C

2011

LOW VITAMIN D EARLY VIROLOGICAL RESPONSE IFN HCVVITAMIN D SVR EVR HCV IFN
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Assessment of hepatitis C virus-RNA clearance under combination therapy for hepatitis C virus genotype 1: performance of transcription-mediated ampli…

2007

Monitoring of HCV-RNA in blood during antiviral therapy is performed mostly by commercially available reverse transcription polymerase chain reaction-based (RT-PCR) assays, with a lower detection limit of 30-50 IU/mL of HCV-RNA. Use of different tests in the pivotal trials of combination therapy has generated some discordance, in terms of predictive value of the early virological response (EVR). To evaluate whether the use of a more sensitive test, as a qualitative assay based on transcription mediated amplification (TMA) with a lower detection limit of 5-10 IU/mL of HCV-RNA, may obtain a better prediction of EVR and of the ultimate virological outcome, we retrospectively evaluated serial s…

Malemedicine.medical_specialtySettore MED/07 - Microbiologia E Microbiologia ClinicaSettore MED/09 - Medicina InternaCombination therapyGenotypeTranscription GeneticTranscription-mediated amplificationHepacivirusAlpha interferonHepacivirusInterferon alpha-2GastroenterologyAntiviral AgentsSensitivity and Specificityantiviral therapy EVR HCV chronic hepatitis HCV-RNA RT-PCR TMAPolyethylene Glycolschemistry.chemical_compoundInterferonPredictive Value of TestsVirologyInternal medicineRibavirinmedicineHumansRetrospective StudiesSettore MED/12 - GastroenterologiaHepatologybiologybusiness.industryReverse Transcriptase Polymerase Chain ReactionRibavirinInterferon-alphaNucleic acid amplification techniqueHepatitis C Chronicbiology.organism_classificationVirologydigestive system diseasesRecombinant ProteinsInfectious DiseasesReal-time polymerase chain reactionTreatment OutcomechemistryRNA ViralDrug Therapy CombinationFemalebusinessNucleic Acid Amplification Techniquesmedicine.drug
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PEG-INTERFERON PLUS RIBAVIRIN IN COMPENSATED HCV CIRRHOSIS WITH PORTAL HYPERTENSION: THE ROLE OF RAPID AND EARLY VIROLOGICAL RESPONSE IN PREDICTING T…

2009

Settore MED/12 - GastroenterologiaSettore MED/07 - Microbiologia E Microbiologia ClinicaPEG IFN/RBV HCV Cirrhosis SVR EVRHCV PEG-Interferon plus Ribavirin Rapid virological response
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